Hernagine type of Aporphine Alkaloids fromAlseodaphne perakensis (1 - 7)

  • Mahfuzah Md Nazimuddin
  • Muhammad Hafiz Husna Hasnan
  • Kartini Ahmad
  • Khaljah Awang
  • Mohd Azlan Nafiah
Keywords: Alseodaphne perakensis, aporphine, oxohernagine, N-methylhernagine

Abstract

A phytochemical study of the stem bark of Alseodaphne perakensis (Lauraceae) had been carried out. The dichloromethane crude extract from stem bark of Alseodaphne perakensis (Lauraceae) yielded two hernagine type of aporphine alkaloids namely oxohernagine and N-methylhernagine. The isolation and purification of these alkaloids were achieved using Column Chromatography (CC) and Preparative Thin Layer Chromatography (PTLC) techniques. The structural elucidations were performed by spectral methods notably Nuclear Magnetic Resonance (NMR) Spectroscopy one-dimentional (1H, 13C and DEPT) and two-dimentional (COSY, HMQC/HSQC and HMBC).

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Published
2014-12-01
How to Cite
Nazimuddin, M., Husna Hasnan, M. H., Ahmad, K., Awang, K., & Nafiah, M. (2014). Hernagine type of Aporphine Alkaloids fromAlseodaphne perakensis (1 - 7). EDUCATUM Journal of Science, Mathematics and Technology, 1(2), 1-7. Retrieved from https://ejournal.upsi.edu.my/index.php/EJSMT/article/view/18