Metabolites Profiling and Fingerprinting of the Ethanolic Extract of Zingiber zerumbet (L.) Roscoe ex Sm.

Authors

  • Nur Zahratun Najah Mohd Razali Atta-ur-Rahman Institute for Natural Product Discovery (AuRIns), Level 9, FF3 Building, Universiti Teknologi MARA, UiTM Selangor, Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor, MALAYSIA
  • Nurunajah Ab Ghani Atta-ur-Rahman Institute for Natural Product Discovery (AuRIns), Level 9, FF3 Building, Universiti Teknologi MARA, UiTM Selangor, Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor, MALAYSIA
  • Nurulfazlina Edayah Rasol Atta-ur-Rahman Institute for Natural Product Discovery (AuRIns), Level 9, FF3 Building, Universiti Teknologi MARA, UiTM Selangor, Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor, MALAYSIA

DOI:

https://doi.org/10.37134/jsml.vol10.1.10.2022

Keywords:

metabolites profiling, fingerprinting, extract, Zingiber zerumbet, bitter ginger

Abstract

Zingiber zerumbet (L.) Roscoe ex Sm. is a herbaceous medicinal plant from the Zingiberaceae family. Previous studies have mainly focused on the essential oils of the plant with little attention to its secondary metabolites. LCMS-Orbitrap is used to analyze ethanolic extract of Z. zerumbet rhizome. Dereplication is a technique applied to identify chemical constituents based on their accurate mass and comparison with custom databases, Dictionary of Natural Products (DNP), and literature using an operating system named MZmine 2.53. In this study, we have identified chemical constituents related to several classes, including flavonoids, terpenoids, diarylheptanoids, terpenes, phenolic compounds, and fatty acids. Our results provide useful information for further isolation and identification of other unknown compounds and mass spectroscopy-based metabolite profiling of Zingiber species.

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Author Biographies

Nurunajah Ab Ghani, Atta-ur-Rahman Institute for Natural Product Discovery (AuRIns), Level 9, FF3 Building, Universiti Teknologi MARA, UiTM Selangor, Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor, MALAYSIA

Faculty of Applied Science, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, MALAYSIA

Nurulfazlina Edayah Rasol, Atta-ur-Rahman Institute for Natural Product Discovery (AuRIns), Level 9, FF3 Building, Universiti Teknologi MARA, UiTM Selangor, Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor, MALAYSIA

Faculty of Applied Science, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, MALAYSIA

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Published

2022-06-28

How to Cite

Mohd Razali, N. Z. N., Ab Ghani, N., & Rasol, N. E. (2022). Metabolites Profiling and Fingerprinting of the Ethanolic Extract of Zingiber zerumbet (L.) Roscoe ex Sm. Journal of Science and Mathematics Letters, 10(1), 97–107. https://doi.org/10.37134/jsml.vol10.1.10.2022

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