Chemical Composition of the Essential Oil of Litsea resinosa Blume and Acetylcholinesterase Activity

Authors

  • Abubakar Siddiq Salihu Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia
  • Nurunajah Ab Ghani Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor, Malaysia
  • Nurulfazlina Edayah Rasol Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor, Malaysia
  • Shamsul Khamis Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia

DOI:

https://doi.org/10.37134/jsml.vol11.1.9.2023

Keywords:

Litsea resinosa, Lauraceae, essential oil, caryophyllene, acetylcholinesterase

Abstract

The essential oil of Litsea resinosa Blume (Lauraceae) was obtained by hydrodistillation and was fully characterized by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). A total of twenty-eight components were identified in the essential oil, which made up 90.8% of the total oil. The essential oil consists mainly of β-caryophyllene (22.5%), α-humulene (15.4%), caryophyllene oxide (9.2%), germacrene D (5.6%), and β-selinene (5.0%). The essential oil showed significant activity against acetylcholinesterase with a percentage inhibition of 72.4%.

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Author Biographies

Abubakar Siddiq Salihu, Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia

Department of Pure and Industrial Chemistry, Faculty of Natural and Applied Sciences, Umaru Musa Yar’adua University, Katsina, Nigeria

Nurunajah Ab Ghani, Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor, Malaysia

Faculty of Applied Sciences, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia

Nurulfazlina Edayah Rasol, Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor, Malaysia

Faculty of Applied Sciences, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia

References

Abdullah SA, Lathiff SMA, Jamil S. (2022). Acetylcholinesterase activity of crude extracts and flavonoids from Artocarpus anisophyllus Miq. and Artocarpus lowii King. Journal of Science and Mathematics Letters, 10(2), 62-66.

Adams RP. (2007). Identification of essential oil components by gas chromatography-mass spectrometry. 4th Ed. Carol Stream (IL): Allured Publishing Corporation.

Ahmad FB, Jantan IB, Bakar BA, Ahmad AS. (2005). A comparative study of the composition of the leaf oils of three Litsea species from Borneo. Journal of Essential Oil Research, 17(3), 323-326.

Azhar MAM, Salleh WMNHW, Khamis S, Ghani NA. (2022). Variation in essential oil composition of three Litsea species from Malaysia. Rivista Italiana Delle Sostanze Grasse, 99(1), 57-61.

Kong DG, Zhao Y, Li GH, Chen BJ, Wang XN, Zhou HL, Lou HX, Ren DM, Shen T. (2015). The genus Litsea in traditional Chinese medicine: an ethnomedical, phytochemical and pharmacological review. Journal of Ethnopharmacology, 164, 256-264.

Salleh WMNHW, Ahmad F, Khong HY, Zulkifli RM. (2016). Chemical composition and biological activities of essential oil of Beilschmiedia pulverulenta. Pharmaceutical Biology, 54(2), 322-330.

Salleh WMNHW, Khamis S, Abed SA. (2021). Characterization of volatile components of Chassalia chartacea and its acetylcholinesterase inhibitory activity. Chemistry of Natural Compounds, 57(2), 376-377.

Salleh WMNHW, Khamis S. (2021). Essential oil of Thottea grandiflora and its lipoxygenase inhibitory activity. Chemistry of Natural Compounds, 57(5), 959-960.

Wong MH, Lim LF, Ahmad FB, Assim ZB. (2014). Antioxidant and antimicrobial properties of Litsea elliptica Blume and Litsea resinosa Blume (Lauraceae). Asian Pacific Journal of Tropical Biomedicine, 4(5), 386-392.

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Published

2023-03-21

How to Cite

Salihu, A. S., Ab Ghani, N., Rasol, N. E., & Khamis, S. (2023). Chemical Composition of the Essential Oil of Litsea resinosa Blume and Acetylcholinesterase Activity. Journal of Science and Mathematics Letters, 11(1), 64–67. https://doi.org/10.37134/jsml.vol11.1.9.2023

Issue

Vol. 11 No. 1 (2023): Journal of Science and Mathematics Letters

Section

Articles

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Copyright (c) 2023 Abubakar Siddiq Salihu, Nurunajah Ab Ghani, Nurulfazlina Edayah Rasol, Shamsul Khamis

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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